Our expert prediction for Friday’s Newcastle Knights vs Penrith Panthers matchup.
The Newcastle Knights will take on the favored Penrith Panthers in National Rugby League (NRL) action at McDonald Jones Stadium on Friday, starting at 4:00AM ET.
Based on the latest simulation results, Dimers’ proven NRL model (see Dimers Pro for full access) predicts the Panthers as the most likely winner of the game.
For expanded analysis of Friday’s matchup, including best bets and picks, visit our interactive Panthers vs. Knights predictions page.

Knights vs. Panthers Prediction: Who Will Win Round 23 Game?
Using innovative machine learning and data analysis, we have simulated the result of Friday’s NRL game between the Panthers and Knights 10,000 times as part of our NRL predictions coverage.
Our leading predictive model gives the Panthers an 80% chance of beating the Knights.
According to our model, the Panthers (-11.5) have a 54% chance of covering the spread, while the 42.5- over/under has a 54% chance of going over.
Panthers vs. Knights Odds
We have sourced the best NRL odds in America for this game, which are listed here:
| Bet Type | Panthers | Knights |
|---|---|---|
| H2H (Moneyline) | -455 | +310 |
| Line (Spread) | -11.5 (-125) | +11.5 (+100) |
| Total | o42.5 (-108) | u42.5 (-120) |
All odds are correct at the time of publication and are subject to change.
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Knights vs. Panthers Game-Day Updates and Essential Details
Friday’s Australian rugby league action between the Knights and Panthers at McDonald Jones Stadium is scheduled to begin at 4:00AM ET.
- Who: Penrith Panthers vs. Newcastle Knights
- Date: Friday, August 8, 2025
- Time: 4:00AM ET/1:00AM PT
- Venue: McDonald Jones Stadium
The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.
Dimers.com’s in-depth preview of Friday’s Panthers vs. Knights matchup includes our prediction, picks and the latest betting odds.
Before making any Panthers vs. Knights picks, be sure to check out the latest NRL predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Panthers, with an 80% win probability, will likely beat the Knights on Friday.
AI and automation have enhanced this article to quickly deliver accurate Panthers vs. Knights insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.







